Exploring the potential biomarkers between stroke and obstructive sleep apnea by WGCNA and machine learning.

Journal: Sleep & breathing = Schlaf & Atmung
Published Date: Jun 20, 2025

Abstract

BACKGROUND: Ischemic stroke (IS) and obstructive sleep apnea (OSA) are highly prevalent disorders with significant societal and individual burdens. OSA exacerbates stroke outcomes, elevates recurrent stroke risk, and impedes functional recovery. Identifying shared biomarkers and elucidating the molecular mechanisms linking IS and OSA have been critical for developing targeted therapies and improving patient prognosis.

Authors

  • Lin Zhou
    Guangdong Province Key Laboratory for Biotechnology Drug Candidates, School of Biosciences and Biopharmaceutics, Guangdong Pharmaceutical University Guangzhou 510006 People's Republic of China zhoulin@gdpu.edu.cn +86-20-39352151 +86-20-39352151.
  • Pengfan Ye
    Department of Neurology, Zhoushan Hospital of Zhejiang Province, Zhoushan, Zhejinag, China.
  • Yiming Wang
    Teaching Resource Information Service Center, Changchun Institute of Education, Changchun, China.

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