OncoE25: an AI model for predicting postoperative prognosis in early-onset stage I-III colon and rectal cancer-a population-based study using SEER with dual-center cohort validation.

Journal: Journal of translational medicine
Published Date:

Abstract

BACKGROUND: Although CRC incidence is declining overall, early-onset colorectal cancers are increasing. No prognostic models currently exist for predicting postoperative survival in Stage I-III early-onset colon or rectal cancer. Such tools are urgently needed to enable individualized risk assessment.

Authors

  • Luyun Yuan
    Department of Oncology, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, No. 164, Lanxi Road, Putuo District, Shanghai, 200062, China.
  • Liyu Wang
    Research Institute of Robotics, Shanghai Jiao Tong University, Shanghai 200240, China.
  • Jiamin Gao
    Department of Oncology, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, No. 164, Lanxi Road, Putuo District, Shanghai, 200062, China.
  • Xin Chen
    University of Nottingham, Nottingham, United Kingdom.
  • Haoyue Wang
    Department of Neurology, Guangdong Key Laboratory for Diagnosis and Treatment of Major Neurological Diseases, National Key Clinical Department, National Key Discipline, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
  • Wei Shan Tan
    Department of Oncology, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, No. 164, Lanxi Road, Putuo District, Shanghai, 200062, China.
  • Kexiang Sun
    Department of Oncology, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, No. 164, Lanxi Road, Putuo District, Shanghai, 200062, China.
  • Yabin Gong
    Oncology Department I, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, No. 110, Ganhe Road, Hongkou District, Shanghai, 200080, China. gongyabin@hotmail.com.
  • Wanli Deng
    Department of Oncology, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, No. 164, Lanxi Road, Putuo District, Shanghai, 200062, China. tcmdwl@163.com.

Keywords

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