Prospective cohort study integrating plasma proteomics and machine learning for early risk prediction of prostate cancer.

Journal: International journal of surgery (London, England)
Published Date:

Abstract

BACKGROUND: Early detection of prostate cancer (PCa) remains a clinical challenge. Plasma proteomics provides a non-invasive tool for identifying individuals at elevated risk prior to symptom onset or PSA elevation.

Authors

  • Yongming Chen
    Frontiers Science Center for Molecular Design Breeding, Key Laboratory of Crop Heterosis and Utilization (MOE), and Beijing Key Laboratory of Crop Genetic Improvement, China Agricultural University, Beijing 100193, China; State Key Laboratory of Wheat Improvement, Peking University Institute of Advanced Agricultural Sciences, Shandong Laboratory of Advanced Agricultural Sciences in Weifang, Shandong 261325, China.
  • Tianxin Long
    State Key Laboratory of Cardiovascular Disease, Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China.
  • Miao Wang
    Public Affairs Department, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
  • Shengjie Liu
    School of Computer Science, Sichuan University, Chengdu 610065, China.
  • Zhengtong Lv
    Department of Urology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China.
  • Yuxiao Jiang
    Beijing Hospital National Center of Gerontology Institute of Geriatric Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
  • Huimin Hou
    Department of Urology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China.
  • Ming Liu
    School of Land Engineering, Chang'an University, Xi'an 710064, China; Xi'an Key Laboratory of Territorial Spatial Information, School of Land Engineering, Chang'an University, Xi'an 710064, China. Electronic address: mingliu@chd.edu.cn.

Keywords

No keywords available for this article.