Preoperative Assessment of Lymph Node Metastasis in Rectal Cancer Using Deep Learning: Investigating the Utility of Various MRI Sequences.

Journal: Annals of surgical oncology
Published Date: Jun 24, 2025

Abstract

PURPOSE: This study aimed to develop a deep learning (DL) model based on three-dimensional multi-parametric magnetic resonance imaging (mpMRI) for preoperative assessment of lymph node metastasis (LNM) in rectal cancer (RC) and to investigate the contribution of different MRI sequences.

Authors

  • Jiayue Zhao
    Digital Medical Research Center, School of Basic Medical Sciences, Fudan University, 138 Yixueyuan Road, Shanghai, 200032, People's Republic of China.
  • Peng Zheng
    Department of Neurology, The First Affiliated Hospital, Chongqing Medical University, Chongqing 400016, China.
  • Teng Xu
    Department of General Surgery, the Affiliated Hospital of Xuzhou Medical University, Xuzhou 221002, China.
  • Qingyang Feng
    Department of Colorectal Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
  • Siyu Liu
    Citromax Flavors Group, Inc., 444 Washington Ave, Carlstadt, NJ, 07072, USA.
  • Yi Hao
    School of Chemistry, Xi'an Jiaotong University, Xi'an 710049, China.
  • Manning Wang
    Digital Medical Research Center, Fudan University, Shanghai, China.
  • Chenxi Zhang
    Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, No. 1 Shuaifuyuan Wangfujing, Dongcheng District, Beijing, 100730, China.
  • Jianmin Xu
    Department of Gastrointestinal Surgery, Affiliated Hospital of Jiangnan University, Wuxi City, Jiangsu Province, 214122, China.

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