Impact of proton versus photon radiotherapy on overall survival in the management of spinal chordoma and mortality risk prediction: a nationwide analysis.

Journal: Journal of neuro-oncology
Published Date:

Abstract

PURPOSE: This study aims to provide a national-level insight into the optimal management of spinal chordoma, a type of rare and complicated malignancy, and to identify effective radiation therapy (RT) strategies for patients with spinal chordoma by comparing photon versus proton therapies.

Authors

  • Abdul Karim Ghaith
    Mayo Clinic Neuro-Informatics Laboratory, Mayo Clinic, Rochester, Minnesota, USA; Department of Neurological Surgery, Mayo Clinic, Rochester, Minnesota, USA.
  • Xinlan Yang
    Department of Neurosurgery, Johns Hopkins University, School of Medicine, 600 N. Wolfe Street/Meyer 5-181, Baltimore, MD, 21287, USA.
  • Taha Khalilullah
    Department of Neurosurgery, Johns Hopkins University, School of Medicine, 600 N. Wolfe Street/Meyer 5-181, Baltimore, MD, 21287, USA.
  • Linda Tang
    Department of Neurosurgery, Johns Hopkins Medicine, Baltimore, MD, USA.
  • Hasan Radwan
    School of Medicine, Department of Neurosurgery, Mayo Clinic, Rochester, MN, USA.
  • Joshua Weinberg
    School of Medicine, Department of Neurosurgery, Ohio State University, Columbus, OH, USA.
  • Jawad Khalifeh
    Department of Neurosurgery, Johns Hopkins University, School of Medicine, 600 N. Wolfe Street/Meyer 5-181, Baltimore, MD, 21287, USA.
  • A Karim Ahmed
    Department of Neurosurgery, Johns Hopkins Medicine, Baltimore, MD, USA.
  • Tej Azad
    Department of Neurosurgery, Johns Hopkins University, School of Medicine, 600 N. Wolfe Street/Meyer 5-181, Baltimore, MD, 21287, USA.
  • Chase Foster
    School of Medicine, Department of Neurosurgery, George Washington, Washington, VA, USA.
  • Nicholas Theodore
    Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Orthopaedic Surgery & Biomedical Engineering, Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address: theodore@jhmi.edu.
  • Kristin J Redmond
    Department of Radiation Oncology, Johns Hopkins University, School of Medicine, Baltimore, MD, USA.
  • Daniel Lubelski

Keywords

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