Death One Hour After Terminal Extubation in Children: Validation of a Machine Learning Model to Predict Cardiac Death After Withdrawal of Life-Sustaining Treatment in a Multicenter Cohort, 2009-2021.

Journal: Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies
Published Date:

Abstract

OBJECTIVES: In the PICU, predicting death within 1 hour after terminal extubation (TE) is valuable in augmenting family counseling and in identifying suitable candidates for organ donation after circulatory determination of death (DCDD). The objective of this study was to train and validate a machine learning model to predict death within 1 hour after TE.

Authors

  • Meredith C Winter
    Department of Anesthesiology Critical Care Medicine, Children's Hospital Los Angeles and Keck School of Medicine, University of Southern California, Los Angeles, CA.
  • Alice X Zhou
    Department of Anesthesiology and Critical Care Medicine, Children's Hospital Los Angeles, Los Angeles, California, USA.
  • Eugene Laksana
    The Laura P. and Leland K. Whittier Virtual Pediatric Intensive Care Unit, Children's Hospital Los Angeles, 4650 Sunset Blvd, Los Angeles, CA 90027, United States. Electronic address: elaksana@chla.usc.edu.
  • Melissa D Aczon
    Laura P. and Leland K. Whittier Virtual Pediatric Intensive Care Unit, Children's Hospital Los Angeles, Los Angeles, CA, USA.
  • David R Ledbetter
  • Michael Avesar
    Division of Pediatric Critical Care Medicine, Loma Linda University Children's Hospital, Loma Linda, CA.
  • Kimberly Burkiewicz
    Pediatric Intensive Care, OSF HealthCare, Children's Hospital of Illinois, Peoria, IL.
  • Harsha K Chandnani
    Division of Pediatric Critical Care Medicine, Loma Linda University Children's Hospital, Loma Linda, CA.
  • Nina Fainberg
    Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, Philadelphia, PA.
  • Stephanie Hsu
    Division of Critical Care Medicine, Department of Pediatrics, The University of Texas Southwestern Medical Center at Dallas, Children's Health Medical Center Dallas, Dallas, TX.
  • Michael C McCrory
    Department of Anesthesiology, Wake Forest University School of Medicine, Winston Salem, NC.
  • Katie R Morrow
    Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL.
  • Anna Noguchi
    Comprehensive Transplant Center, Johns Hopkins Hospital, Baltimore, MD.
  • Caitlin E O'Brien
    Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University, Baltimore, MD.
  • Apoorva Ojha
    Michigan State University College of Human Medicine, Grand Rapids, MI.
  • Charlene Pringle
    Department of Pediatrics, Critical Care Medicine, University of Florida, Gainesville, FL.
  • Patrick A Ross
    Department of Anesthesiology and Critical Care Medicine, Children's Hospital Los Angeles, Los Angeles, CA.
  • Jui Shah
    Division of Pediatric Critical Care Medicine, Loma Linda University Children's Hospital, Loma Linda, CA.
  • Sareen Shah
    Division of Pediatric Critical Care Medicine, Department of Pediatrics Cedars-Sinai Medical Center, Los Angeles, USA.
  • Leonid Shpaner
    UCLA David Geffen School of Medicine, Los Angeles, CA.
  • Linda B Siegel
    Division of Pediatric Critical Care Medicine, Cohen Children's Medical Center, New Hyde Park, NY.
  • Sandeep Tripathi
    Department of Pediatrics, University of Illinois College of Medicine at Peoria/OSF HealthCare, Children's Hospital of Illinois, Peoria, IL.
  • Randall C Wetzel

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