Fecal volatile organic compounds for colorectal cancer detection: A systematic review and meta-analysis.

Journal: Computers in biology and medicine
Published Date:

Abstract

BACKGROUND: Background: Fecal volatile organic compound (VOC) analysis has emerged as a promising non-invasive tool for detecting colorectal cancer (CRC). Despite its reported high diagnostic accuracy, clinical adoption is hindered due to issues like methodological variability, lack of standardization, and limited validation. This systematic review and meta-analysis aim to address these challenges by evaluating the diagnostic performance of fecal VOC analysis and exploring its future potential.

Authors

  • Neha Bhattacharyya
    Electrical and Computer Engineering, McMaster University, Hamilton, Ontario, Canada.
  • Ziya Sastimoglu
    Electrical and Computer Engineering, McMaster University, Hamilton, Ontario, Canada.
  • David Armstrong
    Protein Data Bank in Europe, European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.
  • Ponnambalam Ravi Selvaganapathy
    School of Biomedical Engineering, McMaster University, Hamilton, ON, Canada; Department of Mechanical Engineering, McMaster University, Hamilton, ON, Canada.
  • M Jamal Deen
    Department of Electrical and Computer Engineering and the School of Biomedical Engineering, McMaster University, Hamilton, Ontario, L8S 4K1, Canada. Electronic address: jamal@mcmaster.ca.

Keywords

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