Predicting Retinal Nerve Fiber Layer Thickness From Ocular Hypertension Treatment Study Optic Disc Photographs.

Journal: JAMA ophthalmology
Published Date: Jun 26, 2025

Abstract

IMPORTANCE: Deep learning predictions of retinal nerve fiber layer (RNFL) thickness derived from optic disc photographs may help to determine risk for development of primary open-angle glaucoma (POAG) in patients with ocular hypertension.

Authors

  • James C Liu
    Department of Ophthalmology, Washington University, St Louis, Missouri.
  • Alessandro A Jammal
    Vision, Imaging and Performance (VIP) Laboratory, Duke Eye Center and Department of Ophthalmology, Duke University, Durham, North Carolina.
  • Rafael Scherer
    From the Bascom Palmer Eye Institute (J.A.G., R.S., D.A., S.D.A., O.A., S.P., D.R.C., W.H., M.A., A.J., H.A.K., W.W., M.A.S., R.O., A.G., F.A.M., C.L.K.), University of Miami Miller School of Medicine, Miami, Florida, USA.
  • Douglas R da Costa
    Bascom Palmer Eye Institute, University of Miami, Miami, Florida.
  • Michael Kass
    Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, MO, USA.
  • Mae Gordon
    Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, MO, USA.
  • Felipe A Medeiros
    Duke Eye Center, Department of Ophthalmology, Duke University, Durham, North Carolina, United States.

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