Morphology-based radiological-histological correlation on ultra-high-resolution energy-integrating detector CT using cadaveric human lungs: nodule and airway analysis.

Journal: European radiology
Published Date: Jun 26, 2025

Abstract

OBJECTIVES: To evaluate the depiction capability of fine lung nodules and airways using high-resolution settings on ultra-high-resolution energy-integrating detector CT (UHR-CT), incorporating large matrix sizes, thin-slice thickness, and iterative reconstruction (IR)/deep-learning reconstruction (DLR), using cadaveric human lungs and corresponding histological images.

Authors

  • Akinori Hata
    Department of Radiology, Osaka University Graduate School of Medicine.
  • Masahiro Yanagawa
    Diagnostic and Interventional Radiology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
  • Keisuke Ninomiya
    Department of Diagnostic and Interventional Radiology, Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka, 5650871, Japan.
  • Noriko Kikuchi
    Department of Radiology, Osaka University Graduate School of Medicine.
  • Masako Kurashige
    Department of Pathology, Osaka University Graduate School of Medicine, Osaka, Japan.
  • Daiki Nishigaki
    Department of Artificial Intelligence Diagnostic Radiology, Osaka University Graduate School of Medicine, 2-2, Yamadaoka, Suita, Osaka, 565-0871, Japan.
  • Shuhei Doi
    Department of Diagnostic and Interventional Radiology, Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
  • Kazuki Yamagata
    Department of Artificial Intelligence Diagnostic Radiology, Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
  • Yuriko Yoshida
    Department of Cardiovascular Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
  • Ryo Ogawa
    Agro-Ecological Modeling Group, Institute of Crop Science and Resource Conservation, University of Bonn, Bonn, Germany.
  • Yukiko Tokuda
    Department of Diagnostic and Interventional Radiology, Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka, 5650871, Japan.
  • Eiichi Morii
    Department of Pathology, Osaka University Graduate School of Medicine, Suita-city, Osaka.
  • Noriyuki Tomiyama
    Diagnostic and Interventional Radiology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.

Keywords

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