Alterations in the functional MRI-based temporal brain organisation in individuals with obesity.

Journal: Diabetes, obesity & metabolism
Published Date: Jun 25, 2025

Abstract

AIMS: Obesity is associated with functional alterations in the brain. Although spatial organisation changes in the brains of individuals with obesity have been widely studied, the temporal dynamics in their brains remain poorly understood. Therefore, in this study, we investigated variations in the intrinsic neural timescale (INT) across different degrees of obesity using resting-state functional and diffusion magnetic resonance imaging data from the enhanced Nathan Kline Institute Rockland Sample database.

Authors

  • Seoah Lee
    Department of Mathematics, Inha University, Incheon, Republic of Korea.
  • Jong Young Namgung
    Department of Data Science, Inha University, Incheon, Republic of Korea.
  • Jae-Ho Han
    Department of Pathology, Ajou University School of Medicine, 206 Worldcup-ro, Yeongtong-gu, Suwon-si, Gyeonggi-do, 16499, Republic of Korea.
  • Bo-Yong Park
    Department of Electrical and Computer Engineering, Sungkyunkwan University, Suwon 16419, South Korea; Center for Neuroscience Imaging Research, Institute for Basic Science (IBS), Suwon 16419, South Korea.

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