Plasma proteomics profiles predict the risk of future aortic aneurysm and aortic dissection.

Journal: International journal of surgery (London, England)
Published Date:

Abstract

BACKGROUND: Aortic aneurysms and aortic dissections (AA/AD) are serious vascular conditions that often progress without symptoms and are associated with high mortality, highlighting the need for improved tools to predict the occurrence. This study aims to identify plasma proteins that can predict the risk of future AA/AD events, and to combine these biomarkers with traditional risk factors to construct risk prediction model.

Authors

  • Maohua Li
    Department of Vascular Surgery, The Second Xiangya Hospital of Central South University, Changsha, China.
  • Xiao He
    Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland. xiao.he@bsse.ethz.ch.
  • Wen Gong
    Financial Work Office of Nanchang Municipal People's Government, Jiangxi, Nanchang 330038, China.
  • Shasha Xiao
    Department of Vascular Surgery, The Second Xiangya Hospital of Central South University, Changsha, China.
  • Keyun Fu
    Department of Vascular Surgery, The Second Xiangya Hospital of Central South University, Changsha, China.
  • Qi Qin
    Department of Instrument Science and Engineering, School of Electronic Information and Electrical Engineering, Shanghai Jiao Tong University, Yantai Information Technology Research Institute of SJTU, Shanghai Engineering Research Center for Intelligent diagnosis and treatment instrument, Shanghai 200240, China. Electronic address: qinqi3591@sjtu.edu.cn.
  • Lunchang Wang
    Department of Vascular Surgery, The Second Xiangya Hospital of Central South University, Changsha, China.
  • Xin Li
    Veterinary Diagnostic Center, Shanghai Animal Disease Control Center, Shanghai, China.
  • Chang Shu
    Department of Pharmaceutical Analysis, School of Pharmacy, China Pharmaceutical University, Nanjing 211198, China.
  • Jiehua Li
    College of Polymer Science and Engineering, National Key Laboratory of Advanced Polymer Materials, Med-X center for materials, Sichuan University, Chengdu 610065, China.
  • Zhaowei Zhu
    Department of Urology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, P. R. China.

Keywords

No keywords available for this article.