Bidirectional Prototype-Guided Consistency Constraint for Semi-Supervised Fetal Ultrasound Image Segmentation.

Journal: IEEE journal of biomedical and health informatics
Published Date:

Abstract

Fetal ultrasound (US) image segmentation plays an important role in fetal development assessment, maternal pregnancy management, and intrauterine surgery planning. However, obtaining large-scale, accurately annotated fetal US imaging data is time-consuming and labor-intensive, posing challenges to the application of deep learning in this field. To address this challenge, we propose a semi-supervised fetal US image segmentation method based on bidirectional prototype-guided consistency constraint (BiPCC). BiPCC utilizes the prototype to bridge labeled and unlabeled data and establishes interaction between them. Specifically, the model generates pseudo-labels using prototypes from labeled data and then utilizes these pseudo-labels to generate pseudo-prototypes for segmenting the labeled data inversely, thereby achieving bidirectional consistency. Additionally, uncertainty-based cross-supervision is incorporated to provide additional supervision signals, thereby enhancing the quality of pseudo-labels. Extensive experiments on two fetal US datasets demonstrate that BiPCC outperforms state-of-the-art methods for semi-supervised fetal US segmentation. Furthermore, experimental results on two additional medical segmentation datasets exhibit BiPCC's outstanding generalization capability for diverse medical image segmentation tasks. Our proposed method offers a novel insight for semi-supervised fetal US image segmentation and holds promise for further advancing the development of intelligent healthcare.

Authors

  • Chongwen Lyu
  • Kai Han
    Geneis Beijing Limited Company, Beijing 100102, China.
  • Lu Liu
    College of Pharmacy, Harbin Medical University, Harbin, China.
  • Jun Chen
    Department of Bioengineering, University of California, Los Angeles, Los Angeles, CA 90095, USA.
  • Lele Ma
  • Zheng Pang
  • Zhe Liu
    Interdisciplinary Program in Bioinformatics, Seoul National University, Seoul, Republic of Korea.

Keywords

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