Perivascular Space Burden in Children With Autism Spectrum Disorder Correlates With Neurodevelopmental Severity.

Journal: Journal of magnetic resonance imaging : JMRI
Published Date: Jun 29, 2025

Abstract

BACKGROUND: Cerebral perivascular spaces (PVS) are involved in cerebrospinal fluid (CSF) circulation and clearance of metabolic waste in adult humans. A high number of PVS has been reported in autism spectrum disorder (ASD) but its relationship with CSF and disease severity is unclear.

Authors

  • Giulia Frigerio
    Diagnostic Imaging and Neuroradiology Unit, IRCCS Scientific Institute E. Medea, Bosisio Parini, Lecco, Italy.
  • Gloria Rizzato
    Diagnostic Imaging and Neuroradiology Unit, IRCCS Scientific Institute E. Medea, Bosisio Parini, Lecco, Italy.
  • Denis Peruzzo
    Neuroimaging Unit, Scientific Institute IRCCS "Eugenio Medea", Bosisio Parini (Lecco), Italy; Department of Computer Science, University of Verona, Verona, Italy. Electronic address: denis.peruzzo@lanostrafamiglia.it.
  • Tommaso Ciceri
    NeuroImaging Laboratory, Scientific Institute IRCCS Eugenio Medea, Bosisio Parini, Italy; Department of Information Engineering, University of Padua, Padua, Italy.
  • Elisa Mani
    Child Psychopathology Unit, IRCCS Scientific Institute E. Medea, Bosisio Parini, Lecco, Italy.
  • Fabiola Lanteri
    Child Psychopathology Unit, IRCCS Scientific Institute E. Medea, Bosisio Parini, Lecco, Italy.
  • Valentina Mariani
    Child Psychopathology Unit, IRCCS Scientific Institute E. Medea, Bosisio Parini, Lecco, Italy.
  • Massimo Molteni
  • Nivedita Agarwal
    Diagnostic Imaging and Neuroradiology Unit, IRCCS Scientific Institute E. Medea, Bosisio Parini, Lecco, Italy.

Keywords

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