Obesity Biomarkers: Exploring Factors, Ramification, Machine Learning, and AI-Unveiling Insights in Health Research.

Journal: MedComm
Published Date:

Abstract

Biomarkers play a pivotal role in the detection and management of diseases, including obesity-a growing global health crisis with complex biological underpinnings. The multifaceted nature of obesity, coupled with socioeconomic disparities, underscores the urgent need for precise diagnostic and therapeutic approaches. Recent advances in biosciences, including next-generation sequencing, multi-omics analysis, high-resolution imaging, and smart sensors, have revolutionized data generation. However, effectively leveraging these data-rich technologies to identify and validate obesity-related biomarkers remains a significant challenge. This review bridges this gap by highlighting the potential of machine learning (ML) in obesity research. Specifically, it explores how ML techniques can process complex data sets to enhance the discovery and validation of biomarkers. Additionally, it examines the integration of advanced technologies for understanding obesity mechanisms, assessing risk factors, and optimizing treatment strategies. A detailed discussion is provided on the applications of ML in multi-omics analysis and high-throughput data integration for actionable insights. The academic value of this review lies in synthesizing the latest technological and analytical innovations in obesity research. By providing a comprehensive overview, it aims to guide future studies and foster the development of targeted, data-driven strategies in obesity management.

Authors

  • Ankita Awari
    Department of Food Technology and Nutrition Lovely Professional University Phagwara Punjab India.
  • Deepika Kaushik
    Department of Biotechnology Faculty of Applied Sciences and Biotechnology Shoolini University Solan Himachal Pradesh India.
  • Ashwani Kumar
    Studio of Computational Biology & Bioinformatics, The Himalayan Centre for High-throughput Computational Biology, (HiCHiCoB, A BIC supported by DBT, India)CSIR-Institute of Himalayan Bioresource Technology (CSIR-IHBT), Palampur (HP), India.
  • Emel Oz
    Department of Food Engineering Faculty of Agriculture Ataturk University Erzurum Turkey.
  • Kenan Çadırcı
    Department of Internal Medicine Erzurum Regional Training and Research Hospital Health Sciences University Erzurum Turkey.
  • Charles Brennan
    School of Science RMIT University Melbourne Victoria Australia.
  • Charalampos Proestos
    Laboratory of Food Chemistry Department of Chemistry School of Sciences National and Kapodistrian University of Athens Zografou Athens Greece.
  • Mukul Kumar
    Department of Food Technology and Nutrition Lovely Professional University Phagwara Punjab India.
  • Fatih Oz
    Department of Food Engineering, Faculty of Agriculture, Ataturk University, Erzurum 25240, Turkey.

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