Monitoring of Early Skin Reactions by Optical Coherence Tomography and Dermatoscopy in Patients Receiving Radiation Therapy for Head and Neck Cancer.

Journal: Advances in radiation oncology
Published Date: Jun 10, 2025

Abstract

PURPOSE: Patients with head and neck cancer undergoing radiation therapy (RT) may experience pronounced acute skin reactions. We tested whether optical coherence tomography (OCT) and dermatoscopy could detect and monitor early subclinical RT-induced skin changes and might be used as a noninvasive prediction tool for higher-grade acute toxicity.

Authors

  • Bettina Heise
    Institute for Mathematical Methods in Medicine and Data Based Modelling, Johannes Kepler University (JKU), Linz, Austria.
  • Peter Schlagnitweit
    Institute for Mathematical Methods in Medicine and Data Based Modelling, Johannes Kepler University (JKU), Linz, Austria.
  • Robert Pollak
    Institute for Mathematical Methods in Medicine and Data Based Modelling, Johannes Kepler University (JKU), Linz, Austria.
  • Karoline Felbermayer
    Research Center for Non-Destructive Testing (RECENDT)-GmbH, Linz, Austria.
  • Elisabeth Silberberger
    Department of Radiation Oncology, Ordensklinikum Linz (OKL), Barmherzige Schwestern, Linz, Austria.
  • Lukas Kocik
    Department of Radiation Oncology, Ordensklinikum Linz (OKL), Barmherzige Schwestern, Linz, Austria.
  • Leonhard Trinkl
    Department of Radiation Oncology, Ordensklinikum Linz (OKL), Barmherzige Schwestern, Linz, Austria.
  • David Weinzinger
    Department of Radiation Oncology, Ordensklinikum Linz (OKL), Barmherzige Schwestern, Linz, Austria.
  • Philipp Anderlik
    Department of Radiation Oncology, Ordensklinikum Linz (OKL), Barmherzige Schwestern, Linz, Austria.
  • Andreas Springer
    Department of Radiation Oncology, Ordensklinikum Linz (OKL), Barmherzige Schwestern, Linz, Austria.
  • Marija Geroldinger-Simic
    Department of Dermatology, Ordensklinikum Linz (OKL), Elisabethinen, Linz, Austria.
  • Georg Gruber
    Department of Radiation Oncology, Ordensklinikum Linz (OKL), Barmherzige Schwestern, Linz, Austria.
  • Maximilan Hartl
    Department of ENT, Ordensklinikum Linz (OKL), Barmherzige Schwestern, Linz, Austria.
  • Hans Geinitz
    Department of Radiation Oncology, Ordensklinikum Linz (OKL), Barmherzige Schwestern, Linz, Austria.

Keywords

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