elimination of antimicrobials during ADVanced Organ Support hemodialysis.

Journal: Frontiers in pharmacology
Published Date: Dec 16, 2024

Abstract

BACKGROUND: Acute kidney injury (AKI) requiring continuous renal replacement therapy is common in critically ill patients. The ADVanced Organ Support (ADVOS) system is a novel hemodialysis machine that uses albumin enriched dialysate which allows the removal of protein-bound toxins and drugs. To date, data on antimicrobial removal under ADVOS has not yet been reported.

Authors

  • Christina König
    Department of Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Otto Frey
    Department of Pharmacy, General Hospital of Heidenheim, Heidenheim, Germany.
  • Susanne Himmelein
    ADVITOS GmbH, Munich, Germany.
  • Lisa Mulack
    Department of Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Alexander Brinkmann
    Department of Anesthesiology, Special Pain Management and Intensive Care Medicine, Heidenheim General Hospital, Heidenheim, Germany.
  • Aritz Perez Ruiz de Garibay
    ADVITOS GmbH, Munich, Germany.
  • Tobias Bingold
    ADVITOS GmbH, Munich, Germany.

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