Translational medicine research on the role of key gene network modulation mediated by procyanidin B2 in the precise diagnosis and treatment of multiple sclerosis.

Journal: Journal of translational medicine
Published Date: Jul 1, 2025

Abstract

OBJECTIVE: The present study aimed to investigate the potential role and molecular mechanism of procyanidin B2 (PCB2) in the treatment of multiple sclerosis (MS), with the hope of providing novel strategies for the precision treatment of MS.

Authors

  • Jian Liu
    Department of Rheumatology, The First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, Anhui, China.
  • Meng Pu
    Research Center of Neurobiology, the Key Research Laboratory of Benefiting Qi for Acting Blood Circulation Method to Treat Multiple, Sclerosis of State Administration of Traditional Chinese Medicine, Shanxi University of Chinese Medicine, Jinzhong, 030619, Shanxi Province, China.
  • Di Guo
  • Ying Xiao
    Department of Radiation Oncology, University of Pennsylvania, Philadelphia, PA, USA.
  • Jin-Zhu Yin
    Department of Neurosurgery, The Key Laboratory of Prevention and Treatment of Neurological Disease of Shanxi Provincial Health Commission, Sinopharm Tongmei General Hospital, Datong, 037003, Shanxi Province, China.
  • Dong Ma
    Department of Chemistry, Zhejiang University Hangzhou 310027 P. R. China wujunwu@zju.edu.cn +86-571-87951895.
  • Cun-Gen Ma
    Research Center of Neurobiology, the Key Research Laboratory of Benefiting Qi for Acting Blood Circulation Method to Treat Multiple, Sclerosis of State Administration of Traditional Chinese Medicine, Shanxi University of Chinese Medicine, Jinzhong, 030619, Shanxi Province, China. macungen@sxtcm.edu.cn.
  • Qing Wang
    School of Chemistry and Chemical Engineering, Southwest Petroleum University, Chengdu 610500, China. qwang@163.com.

Keywords

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