Perilesional dominance: radiomics of multiparametric MRI enhances differentiation of IgG4-Related ophthalmic disease and orbital MALT lymphoma.

Journal: BMC medical imaging
Published Date: Jul 1, 2025

Abstract

BACKGROUND: To develop and validate a diagnostic framework integrating intralesional (ILN) and perilesional (PLN) radiomics derived from multiparametric MRI (mpMRI) for distinguishing IgG4-related ophthalmic disease (IgG4-ROD) from orbital mucosa-associated lymphoid tissue (MALT) lymphoma.

Authors

  • Jie Li
    Guangdong-Hong Kong-Macao Greater Bay Area Artificial Intelligence Application Technology Research Institute, Shenzhen Polytechnic University, Shenzhen, China.
  • Chenran Zhou
    Department of Radiology, The Second Hospital of Jilin University, Changchun, Jilin Province, 130041, China.
  • Xiaoxia Qu
    Department of Radiology, Beijing Tongren Hospital, Capital Medical University, No. 1 Dongjiaominxiang Street, Dongcheng District, Beijing, 100730, China; Clinical Center for Eye Tumors, Capital Medical University, Beijing, 100730, China.
  • Lianze Du
    Radiology Department, The Second Hospital of Jilin University, Changchun.
  • Qinghai Yuan
    Radiology Department, The Second Hospital of Jilin University, Changchun.
  • Qinghe Han
    Radiology Department, The Second Hospital of Jilin University, Changchun.
  • Junfang Xian
    Department of Radiology, Beijing Tongren Hospital, Capital Medical University, No. 1 Dongjiaominxiang Street, Dongcheng District, Beijing, 100730, China; Clinical Center for Eye Tumors, Capital Medical University, Beijing, 100730, China. Electronic address: cjr.xianjunfang@vip.163.com.

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