Impact of body mass index on D-dimer diagnostic utility for deep vein thrombosis in patients with cancer: a single-center retrospective analysis.

Journal: International journal of clinical oncology
Published Date: May 12, 2025

Abstract

BACKGROUND: Deep vein thrombosis (DVT) is a common complication in cancer patients associated with significant morbidity and mortality. D-dimer is a widely used screening tool for suspected DVT; however, its accuracy may be influenced by body mass index (BMI). We evaluated whether BMI modified the diagnostic utility of D-dimer levels in patients with cancer and DVT.

Authors

  • Yuya Masuda
    Department of Hematology, Clinical Immunology and Infectious Diseases, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Ehime, 791-0295, Japan.
  • Tatsuya Konishi
    Department of Hematology, Clinical Immunology and Infectious Diseases, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Ehime, 791-0295, Japan. konishi.tatsuya.fv@ehime-u.ac.jp.
  • Yoshihiro Yakushijin
    Cancer Center, Ehime University Hospital, Toon, Japan.
  • Shintaro Yamanaka
    Cancer Center, Ehime University Hospital, Toon, Japan.
  • Shinji Hasebe
    Cancer Center, Ehime University Hospital, Toon, Japan.
  • Jun Yamanouchi
    Department of Hematology, Clinical Immunology and Infectious Diseases, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Ehime, 791-0295, Japan.
  • Katsuto Takenaka
    Department of Hematology, Clinical Immunology and Infectious Diseases, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Ehime, 791-0295, Japan.

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