Insights into radiomics: a comprehensive review for beginners.

Journal: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
Published Date:

Abstract

Radiomics and artificial intelligence (AI) are rapidly evolving, significantly transforming the field of medical imaging. Despite their growing adoption, these technologies remain challenging to approach due to their technical complexity. This review serves as a practical guide for early-career radiologists and researchers seeking to integrate radiomics into their studies. It provides practical insights for clinical and research applications, addressing common challenges, limitations, and future directions in the field. This work offers a structured overview of the essential steps in the radiomics workflow, focusing on concrete aspects of each step, including indicative and practical examples. It covers the main steps such as dataset definition, image acquisition and preprocessing, segmentation, feature extraction and selection, and AI model training and validation. Different methods to be considered are discussed, accompanied by summary diagrams. This review equips readers with the knowledge necessary to approach radiomics and AI in medical imaging from a hands-on research perspective.

Authors

  • Francesco Mariotti
    Department of Clinical, Special and Dental Sciences, University Politecnica delle Marche, Via Tronto, 10/A, 60126, Ancona, Italy.
  • Andrea Agostini
    Department of Clinical, Special and Dental Sciences, University Politecnica delle Marche, Via Tronto, 10/A, 60126, Ancona, Italy.
  • Alessandra Borgheresi
    Department of Clinical, Special and Dental Sciences, University Politecnica delle Marche, Via Tronto, 10/A, 60126, Ancona, Italy. alessandra.borgheresi@gmail.com.
  • Marzia Marchegiani
    School of Radiology, University Politecnica delle Marche, Via Tronto, 10/A, 60126, Ancona, Italy.
  • Alice Zannotti
    School of Radiology, University Politecnica delle Marche, Via Tronto, 10/A, 60126, Ancona, Italy.
  • Gloria Giacomelli
    School of Radiology, University Politecnica delle Marche, Via Tronto, 10/A, 60126, Ancona, Italy.
  • Luca Pierpaoli
    School of Radiology, University Politecnica delle Marche, Via Tronto, 10/A, 60126, Ancona, Italy.
  • Elisabetta Tola
    School of Radiology, University Politecnica delle Marche, Via Tronto, 10/A, 60126, Ancona, Italy.
  • Elena Galiffa
    School of Radiology, University Politecnica delle Marche, Via Tronto, 10/A, 60126, Ancona, Italy.
  • Andrea Giovagnoni
    Department of Clinical, Special and Dental Sciences, University Politecnica delle Marche, Via Tronto, 10/A, 60126, Ancona, Italy.

Keywords

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