Novel CAC Dispersion and Density Score to Predict Myocardial Infarction and Cardiovascular Mortality.

Journal: Circulation. Cardiovascular imaging
Published Date:

Abstract

BACKGROUND: Coronary artery calcification (CAC) provides robust prediction for major adverse cardiovascular events (MACE), but current techniques disregard plaque distribution and protective effects of high CAC density. We investigated whether a novel CAC-dispersion and density (CAC-DAD) score will exhibit superior prognostic value compared with the Agatston score (AS) for MACE prediction.

Authors

  • Gavin Huangfu
    Department of Cardiology, Fiona Stanley Hospital, Perth, WA, Australia (G.H., A.R.I., H.S., L.D., G.D.).
  • Abdul R Ihdayhid
    Department of Cardiology, Fiona Stanley Hospital, Perth, WA, Australia (G.H., A.R.I., H.S., L.D., G.D.).
  • Simon Kwok
    Artrya Ltd, Perth, WA, Australia (S.K., J.K., K.N.).
  • John Konstantopoulos
    Artrya Ltd, Perth, WA, Australia (S.K., J.K., K.N.).
  • Kai Niu
    Key Laboratory of Universal Wireless Communations, Ministry of Education, Beijing University of Posts and Telecommunications, Beijing 100876, China.
  • Juan Lu
    Yunnan Agricultural University, Kunming, China.
  • Harry Smallbone
    Fiona Stanley Hospital, Perth, Western Australia, Australia.
  • Gemma A Figtree
    University of Sydney, NSW, Australia (G.A.F., C.K.C., S.M.G.).
  • Clara K Chow
    The University of Sydney, Sydney Medical School, Sydney, New South Wales, Australia.
  • Lawrence Dembo
    Department of Cardiology, Fiona Stanley Hospital, Perth, WA, Australia (G.H., A.R.I., H.S., L.D., G.D.).
  • Brendan Adler
    Envision Medical Imaging, Perth, WA, Australia (L.D., B.A.).
  • Christian Hamilton-Craig
    The Prince Charles Hospital, Brisbane, QLD, Australia; Centre for Advanced Imaging, University of Queensland and Griffith University School of Medicine, QLD, Australia.
  • Stuart M Grieve
    Sydney Medical School, University of Sydney, Sydney, NSW, Australia.
  • Matthew T V Chan
    Department of Anaesthesia and Intensive Care and Peter Hung Pain Research Institute, The Chinese University of Hong Kong, Hong Kong.
  • Craig Butler
    University of Alberta, Edmonton, Canada (C.B.).
  • Vikas Tandon
    McMaster University, Hamilton, ON, Canada (V.T., W.S., P.J.D., T.S.).
  • Peter Nagele
    The University of Chicago, IL (P.N.).
  • Pamela K Woodard
    Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO (P.K.W.).
  • Marko Mrkobrada
    Western University, London, ON, Canada (M.M.).
  • Wojciech Szczeklik
    Centre for Intensive Care and Perioperative Medicine, Jagiellonian University Medical College, Kraków, Poland.
  • Yang Faridah Abdul Aziz
    Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia (Y.F.A.A.).
  • Bruce Biccard
    University of Cape Town, South Africa (B.B.).
  • Philip James Devereaux
    McMaster University, Hamilton, ON, Canada (V.T., W.S., P.J.D., T.S.).
  • Tej Sheth
    Division of Cardiology, Hamilton General Hospital, Hamilton Health Sciences, McMaster University, Hamilton, ON, Canada.
  • Girish Dwivedi
    Department of Medicine, The University of Western Australia, 35 Stirling Highway, CRAWLEY Western Australia 6009, Australia.
  • Benjamin J W Chow
    Department of Medicine, Division of Cardiology, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, ON K1Y 4W7, Canada.

Keywords

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