Identification and verification of feature biomarkers associated with CD14 monocytes in type 1 diabetes.

Journal: Journal of diabetes investigation
Published Date: Jul 5, 2025

Abstract

AIMS/INTRODUCTION: Monocytes contribute to the immune dysregulation of pancreatic islets in Type 1 diabetes mellitus (T1D). This study aims to identify the feature genes of CD14 monocytes in T1D, which might offer a new perspective on immune dysregulation and potential therapeutic targets in T1D.

Authors

  • Jin Huang
    College of Life Science, Yangtze University, Jingzhou, Hubei 434023, P. R. China; Institute of Agricultural Products Processing, Jiangsu Academy of Agricultural Sciences, Nanjing, 210014, PR China.
  • Yu Ding
    College of Economics and Management, Nanjing University of Aeronautics and Astronautics, Nanjing, 211106, China.
  • Tong Yu
  • Shanshan Chen
    School of Life Sciences, Jilin University, Changchun, China.
  • Jinrong He
    Cancer Research Institute of Wuhan, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
  • Lifeng Shi
    Department of Medical Laboratory, The Central Hospital of Wuhan, Huazhong University of Science and Technology, Wuhan, China.
  • Xiuling Wang
    Department of Medical Laboratory, The Central Hospital of Wuhan, Huazhong University of Science and Technology, Wuhan, China.

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