Coumarin hybrids: dual-target candidates for future antimicrobial and antitubercular therapies.

Journal: Future medicinal chemistry
Published Date: May 12, 2025

Abstract

AIMS: This study aimed to synthesize, characterize, and evaluate the antimicrobial and antitubercular activities of two novel series of coumarin-based derivatives (Series 5 and Series 9), focusing on their structure-activity relationship (SAR) and molecular docking interactions with key bacterial enzymes.

Authors

  • Abhay Bavishi
    Department of Chemistry, Christ College, Rajkot, India.
  • Hardev Vala
    Department of Chemistry, Saurashtra University, Rajkot, India.
  • Shailesh Thakrar
    Department of Chemistry, Christ College, Rajkot, India.
  • Sagar Swami
    Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.
  • Dhiman Sarkar
    Combi-Chem Bio-Resource Center, Organic Chemistry Division, CSIR-National Chemical Laboratory, Pune, India.
  • Rushit Shukla
    Department of Microbiology, Christ College, Rajkot, India.
  • Jignesh Kamdar
    In Silico Lab, Department of Microbiology, School of Science, RK University, Rajkot, India.
  • Anamik Shah
    Department of Chemistry, Saurashtra University, Rajkot, India.

Keywords

No keywords available for this article.

External Resources

Popular Topics
Recent Journals