Cardiac amyloidosis detection from a single echocardiographic video clip: a novel artificial intelligence-based screening tool.

Journal: European heart journal
Published Date:

Abstract

BACKGROUND AND AIMS: Accurate differentiation of cardiac amyloidosis (CA) from phenotypic mimics remains challenging using current clinical and echocardiographic techniques. The accuracy of a novel artificial intelligence (AI) screening algorithm for echocardiography-based CA detection was assessed.

Authors

  • Jeremy A Slivnick
    University of Chicago Medical Center, Chicago, Illinois.
  • Will Hawkes
    Ultromics Limited, Oxford, United Kingdom.
  • Jorge Oliveira
  • Gary Woodward
    Ultromics Ltd, Oxford, United Kingdom.
  • Ashley Akerman
    Ultromics Limited, Oxford, United Kingdom.
  • Alberto Gomez
    Ultromics Ltd, Oxford, United Kingdom.
  • Izhan Hamza
    Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minn.
  • Viral K Desai
    Department of Cardiovascular Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.
  • Zachary Barrett-O'Keefe
    Department of Cardiovascular Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.
  • Martha Grogan
    Department of Cardiovascular Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
  • Angela Dispenzieri
    Division of Hematology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
  • Christopher G Scott
    Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA.
  • Halley N Davison
    Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.
  • Juan Cotella
    University of Chicago, Chicago, IL, 5758 South Maryland Avenue, M.C. 9067, Chicago, IL 60637, USA.
  • Mathew Maurer
    Seymour, Paul, and Gloria Milstein Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center/New York-Presbyterian Hospital, NY (A.L., G.M., E.D., T.M., M.M., A.J.E., D.K., S.H., Q.L., V.A., M. Lebehn, M. Leon, R.H., P.E., T.J.P.).
  • Stephen Helmke
    Division of Cardiology, Columbia University, 622 West 168th Street, PH12-134, New York, NY 10032, USA.
  • Marielle Scherrer-Crosbie
    Division of Cardiovascular Medicine, University of Pennsylvania, Hospital of the University of Pennsylvania, Room 11-131, 11th Floor South Pavilion, 3400 Civic Center Blvd., Philadelphia, PA 19104, USA.
  • Marwa Soltani
    Division of Cardiovascular Medicine, University of Pennsylvania, Hospital of the University of Pennsylvania, Room 11-131, 11th Floor South Pavilion, 3400 Civic Center Blvd., Philadelphia, PA 19104, USA.
  • Akash Goyal
    Division of Cardiovascular Medicine, Ohio State University, 473 W. 12th Ave, Suite 200, Columbus, OH 43210, USA.
  • Karolina M Zareba
    Division of Cardiovascular Medicine, Ohio State University, 473 W. 12th Ave, Suite 200, Columbus, OH 43210, USA.
  • Richard K Cheng
    Division of Cardiology, University of Washington, 1959 NE Pacific Street, Box 356422, Seattle, WA 98195-6422, USA.
  • James N Kirkpatrick
    University of Washington, Seattle, WA, USA.
  • Tetsuji Kitano
    Department of Cardiology and Nephrology, Wakamatsu Hospital, University of Occupational and Environmental Health, Kitakyushu, Japan.
  • Masaaki Takeuchi
    Department of Laboratory and Transfusion Medicine, University Hospital, University of Occupational and Environmental Health, Kitakyushu, Japan.
  • Viviane Tiemi Hotta
    Clinical Unity of Cardiomyopathies, Heart Institute (InCor), Av. Dr. Enéas Carvalho de Aguiar, 44, Cerqueira Cezar, Sao Paolo CEP: 05403/000, Brazil.
  • Marcelo Luiz Campos Vieira
    Clinical Unity of Cardiomyopathies, Heart Institute (InCor), Av. Dr. Enéas Carvalho de Aguiar, 44, Cerqueira Cezar, Sao Paolo CEP: 05403/000, Brazil.
  • Pablo Elissamburu
    Division of Cardiovascular Imaging, ICBA, Blanco Encalada 1543 street - C1428DCO, CABA, Argentina.
  • Ricardo E Ronderos
    Division of Cardiovascular Imaging, ICBA, Blanco Encalada 1543 street - C1428DCO, CABA, Argentina.
  • Aldo Prado
    Centro Privado de Cardiologia, Yerba Buena, Virgen de la Merced 550, Tucumán, Argentina.
  • Efstratios Koutroumpakis
    Department of Cardiology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, United States.
  • Anita Deswal
    Michael E. DeBakey VA Medical Center & Baylor College of Medicine, Houston, TX (B.B., A.D.).
  • Amit Pursnani
    Cardiology, Endeavor NorthShore Cardiovascular Institute, Evanston, IL (A.P.).
  • Nitasha Sarswat
    University of Chicago, Chicago, IL, 5758 South Maryland Avenue, M.C. 9067, Chicago, IL 60637, USA.
  • Amit R Patel
    Cardiac Imaging Center, University of Chicago Medical Center, Chicago, Illinois.
  • Karima Addetia
    Department of Medicine, University of Chicago Medical Center, 5758 South Maryland Ave, MC 9067 Room 5513, Chicago, IL, USA.
  • Frederick L Ruberg
    Division of Cardiovascular Medicine, Boston University Chobanian & Avedisian School of Medicine, 821 Collamore Building, 72 East Concord Street, Boston, MA 02118-2308, USA.
  • Michael Randazzo
    University of Chicago Medical Center, Chicago, Illinois.
  • Federico M Asch
    MedStar Health Research Institute, Washington DC (F.M.A.).
  • Jamie O'Driscoll
    Ultromics Ltd, Oxford, United Kingdom.
  • Nora Al-Roub
    Richard A. and Susan F. Smith Center for Outcomes Research in Cardiology, Division of Cardiology, Beth Israel Deaconess Medical Center, Boston, MA, USA.
  • Jordan B Strom
    Richard A. and Susan F. Smith Center for Outcomes Research in Cardiology, Division of Cardiology, Beth Israel Deaconess Medical Center, Boston, MA, USA. jstrom@bidmc.harvard.edu.
  • Liam Kidd
    Brigham & Women's Hospital, 75 Francis Street, Boston, MA 02115, USA.
  • Sarah Cuddy
    Brigham & Women's Hospital, 75 Francis Street, Boston, MA 02115, USA.
  • Ross Upton
    Ultromics Ltd, Oxford, United Kingdom.
  • Roberto M Lang
    Cardiac Imaging Center, University of Chicago Medical Center, Chicago, Illinois.
  • Patricia A Pellikka
    Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota, USA.

Keywords

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