Recent developments with pH-responsive lyotropic liquid crystalline lipid nanoparticles for targeted bioactive agent delivery.

Journal: Expert opinion on drug delivery
Published Date: Jul 9, 2025

Abstract

INTRODUCTION: Lyotropic liquid crystalline lipid nanoparticles (LNPs) are a platform technology with broad-ranging potential in bioactive agent delivery applications. Their biomimetic properties impart the capacity to encapsulate large biomolecules and to overcome biological barriers.

Authors

  • Natinael Koyra
    School of Science, STEM College, RMIT University, Melbourne, Victoria, Australia.
  • Haitao Yu
    Department of Fundamental Medicine, Wuxi School of Medicine, Jiangnan University, Wuxi 214122, Jiangsu, China.
  • Calum J Drummond
    School of Science, STEM College, RMIT University, Melbourne, Victoria, Australia.
  • Jiali Zhai
    School of Science, STEM College, RMIT University, Melbourne, Victoria, Australia.
  • Brendan Dyett
    School of Science, STEM College, RMIT University, Melbourne, Victoria, Australia.

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