The two cut-offs approach for plasma p-tau217 in detecting Alzheimer's disease in subjective cognitive decline and mild cognitive impairment.

Journal: Alzheimer's & dementia (Amsterdam, Netherlands)
Published Date:

Abstract

BACKGROUND: The study aimed to explore the applicability of plasma phosphorylated tau (p-tau)217 in identifying patients with subjective cognitive decline (SCD) and mild cognitive impairment (MCI) carrying Alzheimer's disease (AD) pathology in real-world settings.

Authors

  • Giulia Giacomucci
    Department of Neuroscience, Psychology, Drug Research and Child Health University of Florence Florence Italy.
  • Chiara Crucitti
    Department of Neuroscience, Psychology, Drug Research and Child Health University of Florence Florence Italy.
  • Assunta Ingannato
    Department of Neuroscience, Psychology, Drug Research and Child Health University of Florence Florence Italy.
  • Valentina Moschini
    Research and Innovation Centre for Dementia-CRIDEM, AOU Careggi Florence Italy.
  • Silvia Bagnoli
    Department of Neuroscience, Psychology, Drug Research and Child Health University of Florence Florence Italy.
  • Federico Emanuele Pozzi
    Department of Neurology, Fondazione IRCCS San Gerardo dei Tintori Monza Italy.
  • Elisa Marcantelli
    Department of Neuroscience, Psychology, Drug Research and Child Health University of Florence Florence Italy.
  • Sonia Padiglioni
    Research and Innovation Centre for Dementia-CRIDEM, AOU Careggi Florence Italy.
  • Carmen Morinelli
    Research and Innovation Centre for Dementia-CRIDEM, AOU Careggi Florence Italy.
  • Salvatore Mazzeo
    Vita-Salute San Raffaele University Milan Italy.
  • Sandro Sorbi
    Department of Neuroscience, Psychology, Drug Research and Child Health University of Florence Florence Italy.
  • Valentina Berti
    Department of Biomedical Experimental and Clinical Sciences "Mario Serio," University of Florence Florence Italy.
  • Benedetta Nacmias
    Department of Neuroscience, Psychology, Drug Research and Child Health University of Florence Florence Italy.
  • Valentina Bessi
    Department of Neuroscience, Psychology, Drug Research and Child Health University of Florence Florence Italy.

Keywords

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