Automated MRI protocoling in neuroradiology in the era of large language models.

Journal: La Radiologia medica
Published Date: Jul 11, 2025

Abstract

PURPOSE: This study investigates the automation of MRI protocoling, a routine task in radiology, using large language models (LLMs), comparing an open-source (LLama 3.1 405B) and a proprietary model (GPT-4o) with and without retrieval-augmented generation (RAG), a method for incorporating domain-specific knowledge.

Authors

  • Lara Noelle Reiner
    Department of Neuroradiology, Charité-Universitätsmedizin Berlin/Berlin Institute of Health, Charitéplatz 1, 10117, Berlin, Germany.
  • Moudather Chelbi
    Department of Neuroradiology, Charité-Universitätsmedizin Berlin/Berlin Institute of Health, Charitéplatz 1, 10117, Berlin, Germany.
  • Leonard Fetscher
    Department of Neuroradiology, Charité-Universitätsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Germany.
  • Juliane C Stöckel
    Department of Neuroradiology, Charité-Universitätsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Germany.
  • Christoph Csapó-Schmidt
    Department of Neuroradiology, Charité-Universitätsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Germany.
  • Shakhnaz Guseynova
    Department of Neuroradiology, Charité-Universitätsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Germany.
  • Fares Al Mohamad
    Department of Radiology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, 10117 Berlin, Germany (F.A.M., L.D., F.D., L.R., K.D., H.H., L.X., F.B.). Electronic address: fares.al-mohamad@charite.de.
  • Keno Kyrill Bressem
    Department of Radiology and Nuclear Medicine, German Heart Center Munich, Lazarettstraße 36, 80636 Munich, Germany (K.K.B.).
  • Jawed Nawabi
    Department of Diagnostic and Interventional Neuroradiology, University Medical Center Hamburg Eppendorf, Hamburg, Germany. jawed.nawabi@charite.de.
  • Eberhard Siebert
    Department of Neuroradiology, Charité-Universitätsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Germany.
  • Mike P Wattjes
    Department of Radiology & Nuclear Medicine, Neuroscience Campus Amsterdam, VUmc MS Center Amsterdam, VU University Medical Center Amsterdam, Amsterdam, The Netherlands.
  • Michael Scheel
    Charité - Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health (BIH), Department of Neurology, 10117 Berlin, Germany; Charité - Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health (BIH), NeuroCure Clinical Research Center, 10117 Berlin, Germany; Charité - Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universitt zu Berlin, Berlin Institute of Health (BIH), Department of Neuroradiology, 10117 Berlin, Germany.
  • Aymen Meddeb
    Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Klinik für Radiologie, Hindenburgdamm 30, 12203 Berlin, Germany.

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