Advancing Early Detection of Major Depressive Disorder Using Multisite Functional Magnetic Resonance Imaging Data: Comparative Analysis of AI Models.
Journal:
JMIRx med
Published Date:
Jul 15, 2025
Abstract
BACKGROUND: Major depressive disorder (MDD) is a highly prevalent mental health condition with significant public health implications. Early detection is crucial for timely intervention, but current diagnostic methods often rely on subjective clinical assessments, leading to delayed or inaccurate diagnoses. Advances in neuroimaging and machine learning (ML) offer the potential for objective and accurate early detection.
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