Proteomic technologies for profiling cell-membrane/secretome interactions in brain metastatic cancer progression.
Journal:
Expert review of proteomics
Published Date:
Jul 23, 2025
Abstract
INTRODUCTION: The ability of cancer cells to disseminate from the primary tumor and form metastatic lesions frequently leads to fatal outcomes. Recently, however, it has been recognized that this process is driven by complex interactions between the cancer and the neighboring cells, and, overall, made possible by a supportive tumor microenvironment. The emergence of high-throughput technologies is expected to bring much-needed clarity to unraveling the players and intricate communication pathways that promote metastatic progression.
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