Diagnostics of Autoimmune Hepatitis Enabled by Non-Invasive Clinical Proteomics.

Journal: Alimentary pharmacology & therapeutics
Published Date: Jul 17, 2025

Abstract

BACKGROUND: Autoimmune hepatitis (AIH) may be difficult to diagnose and distinguish clinically and biochemically from other chronic liver diseases like metabolic dysfunction-associated steatotic liver disease (MASLD).

Authors

  • Anne-Sofie Houlberg Jensen
    Department of Clinical Biochemistry, Copenhagen University Hospital-Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark.
  • Henriette Ytting
    Gastro Unit, Copenhagen University Hospital-Amager and Hvidovre Hospital, Hvidovre, Denmark.
  • Annelaura Bach Nielsen
    Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen N, Denmark.
  • Mikkel Parsberg Werge
    Gastro Unit, Copenhagen University Hospital-Amager and Hvidovre Hospital, Hvidovre, Denmark.
  • Elias Badal Rashu
    Gastro Unit, Copenhagen University Hospital-Amager and Hvidovre Hospital, Hvidovre, Denmark.
  • Liv Eline Hetland
    Gastro Unit, Copenhagen University Hospital-Amager and Hvidovre Hospital, Hvidovre, Denmark.
  • Mira Thing
    Gastro Unit, Copenhagen University Hospital-Amager and Hvidovre Hospital, Hvidovre, Denmark.
  • Puria Nabilou
    Gastro Unit, Copenhagen University Hospital-Amager and Hvidovre Hospital, Hvidovre, Denmark.
  • Johan Burisch
    Gastro Unit, Copenhagen University Hospital-Amager and Hvidovre Hospital, Hvidovre, Denmark.
  • Anders Ellekær Junker
    Gastro Unit, Copenhagen University Hospital-Amager and Hvidovre Hospital, Hvidovre, Denmark.
  • Lise Hobolth
    Gastro Unit, Copenhagen University Hospital-Amager and Hvidovre Hospital, Hvidovre, Denmark.
  • Christian Mortensen
    Gastro Unit, Copenhagen University Hospital-Amager and Hvidovre Hospital, Hvidovre, Denmark.
  • Flemming Tofteng
    Gastro Unit, Copenhagen University Hospital-Amager and Hvidovre Hospital, Hvidovre, Denmark.
  • Flemming Bendtsen
    Gastro Unit, Copenhagen University Hospital-Amager and Hvidovre Hospital, Hvidovre, Denmark.
  • Soren Möller
    Open Patient Data Explorative Network, OPEN, Odense University Hospital and Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
  • Mogens Vyberg
    Department of Pathology, Copenhagen University Hospital-Amager and Hvidovre Hospital, Hvidovre, Denmark.
  • Reza Rafiolsadat Serizawa
    Department of Pathology, Copenhagen University Hospital-Amager and Hvidovre Hospital, Hvidovre, Denmark.
  • Marie Winther-Sørensen
    Department of Clinical Biochemistry, Copenhagen University Hospital-Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark.
  • Jesper Sloth Kellemann
    Department of Clinical Biochemistry, Copenhagen University Hospital-Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark.
  • Lise Lotte Gluud
    Gastro Unit, Copenhagen University Hospital-Amager and Hvidovre Hospital, Hvidovre, Denmark.
  • Nicolai Jacob Wewer Albrechtsen
    Department of Clinical Biochemistry, Copenhagen University Hospital-Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark.

Keywords

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