An overview of focused ultrasound as a treatment option for gliomas.

Journal: Expert review of neurotherapeutics
Published Date: Jul 20, 2025

Abstract

INTRODUCTION: High-grade gliomas remain difficult to treat due to their infiltrative growth, therapeutic resistance, and the restrictive blood-brain barrier (BBB). Focused ultrasound (FUS) offers a noninvasive method to transiently disrupt the BBB, enhancing the delivery of therapeutics to the tumor site.

Authors

  • Grace Hey
    University of Florida College of Medicine, Gainesville, Florida, USA.
  • Chloe DeYoung
    University of Florida College of Medicine, Gainesville, FL, USA.
  • Abeer Dagra
    Lillian S. Wells Department of Neurosurgery, University of Florida College of Medicine, Gainesville, FL, USA.
  • Wiley Gillam
    University of Florida College of Medicine, Gainesville, FL, USA.
  • Brandon Lucke-Wold
    1Lillian S. Wells Department of Neurosurgery.

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