Development and Validation of the Relational Tissue Altered (RTA) Index: Applied Artificial Intelligence for the Assessment of Structural Impact from Laser Vision Correction.

Journal: Ophthalmology and therapy
Published Date: Jul 19, 2025

Abstract

INTRODUCTION: A retrospective case-control study was carried out to develop a predictive computational model to objectively and accurately represent the impact of laser vision correction (LVC) on the corneal structure. This study involved data from 3278 eyes (1690 patients) that remained stable after refractive surgery and 105 eyes (66 patients) that developed postoperative ectasia.

Authors

  • Aydano P Machado
    Department of Ophthalmology of Federal University of São Paulo, São Paulo, Brazil.
  • Louise Pellegrino G Esporcatte
    Department of Ophthalmology, Federal University of São Paulo, São Paulo, Brazil.
  • Marcella Q Salomão
    Department of Ophthalmology of Federal University of São Paulo, São Paulo, Brazil; Rio de Janeiro Corneal Tomography and Biomechanical Study Group, Rio de Janeiro, Brazil; Instituto de Olhos Renato Ambrósio, Rio de Janeiro, Brazil.
  • Bernardo T Lopes
    Department of Ophthalmology of Federal University of São Paulo, São Paulo, Brazil; Rio de Janeiro Corneal Tomography and Biomechanical Study Group, Rio de Janeiro, Brazil; Instituto de Olhos Renato Ambrósio, Rio de Janeiro, Brazil; School of Engineering, University of Liverpool, Liverpool, United Kingdom. Electronic address: blopesmed@gmail.com.
  • João Marcelo A G Lyra
    Brazilian Artificial Intelligence Networking in Medicine-BrAIN, Maceió, Brazil.
  • Renato Ambrosio
    Brazilian Study Group of Artificial Intelligence and Corneal Analysis - BrAIN, Rio de Janeiro & Maceió, Brazil.

Keywords

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