Machine Learning for Detecting Iron Deficiency through Comprehensive Blood Analysis.

Journal: Clinical chemistry
Published Date: Jul 18, 2025

Abstract

BACKGROUND: Iron deficiency (ID) is a prevalent global health issue with a major impact on well-being. Early detection of ID is crucial but challenging due to its nonspecific symptoms and the limitations of traditional diagnostic tests, which are impractical for large-scale screening. This study proposes a machine learning (ML) approach using complete blood count (CBC) data and cell population data (CPD) for detecting ID in the general population.

Authors

  • Yu-Hsin Chang
    Department of Emergency Medicine, China Medical University Hospital, No. 2, Yude Rd., North Dist, Taichung City, 40447, Taiwan.
  • Chia-Yu Chen
    School of Medicine, College of Medicine, China Medical University, Taichung City, Taiwan.
  • Chiung-Tzu Hsiao
    Departments of Laboratory Medicine, China Medical University Hospital, China.
  • Yu-Chang Chang
    Department of Laboratory Medicine, China Medical University Hospital, China Medical University, China Medical University, Taichung City, Taiwan.
  • Hsin-Yu Lai
  • Hsiu-Hsien Lin
    Department of Laboratory Medicine, China Medical University Hospital, China Medical University, Taichung, Taiwan.
  • Ya-Lun Wu
    Artificial Intelligence Center, China Medical University Hospital, No. 2, Yude Rd, North Dist, Taichung, Taiwan.
  • Chien-Chih Chen
    Department of Surgery, Koo Foundation Sun Yat-Sen Cancer Center, Taipei, Taiwan.
  • Lin-Chen Hsu
    Department of Laboratory, An-Nan Hospital, China Medical University, Tainan City, Taiwan.
  • Tzu-Ting Chen
    School of Medicine, College of Medicine, China Medical University, Taichung City, Taiwan.
  • Hong-Mo Shih
    Department of Emergency Medicine, China Medical University Hospital, Taichung, Taiwan; School of Medicine, College of Medicine, China Medical University, Taichung, Taiwan. Electronic address: homoe042002@hotmail.com.
  • Po-Ren Hsueh
    Department of Laboratory Medicine, China Medical University Hospital, China Medical University, Taichung, Taiwan; Division of Infectious Diseases, Department of Internal Medicine, China Medical University Hospital, China Medical University, Taichung, Taiwan. Electronic address: hsporen@gmail.com.
  • Der-Yang Cho
    Department of Neurosurgery, China Medical University Hospital, Taichung, Taiwan.

Keywords

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