Artificial intelligence-enabled electrocardiography and echocardiography to track preclinical progression of transthyretin amyloid cardiomyopathy.

Journal: European heart journal
Published Date:

Abstract

BACKGROUND AND AIMS: The diagnosis of transthyretin amyloid cardiomyopathy (ATTR-CM) requires advanced imaging, precluding large-scale preclinical testing. Artificial intelligence (AI)-enabled transthoracic echocardiography (TTE) and electrocardiography (ECG) may provide a scalable strategy for preclinical monitoring.

Authors

  • Evangelos K Oikonomou
    Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Headley Way, Oxford, UK.
  • Veer Sangha
    Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.
  • Sumukh Vasisht Shankar
    Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.
  • Andreas Coppi
  • Harlan M Krumholz
    Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.
  • Khurram Nasir
    Houston Methodist DeBakey Heart & Vascular Center, Houston, Texas, US.
  • Edward J Miller
    Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, United States.
  • Cesia Gallegos Kattan
    Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.
  • Mouaz H Al-Mallah
    Division of Cardiovascular Medicine, Henry Ford Hospital, Detroit, Michigan; King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, King AbdulAziz Cardiac Center, Ministry of National Guard, Health Affairs, Riyadh, Saudi Arabia. Electronic address: mouaz74@gmail.com.
  • Sadeer Al-Kindi
    Division of Cardiology, Department of Medicine (S.A.-K., F.N., G.F.A., M.A.C., D.I.S., M.S.A., J.A.M., S.G.T.), Case Western Reserve University, Harrington Heart and Vascular Institute, and University Hospitals Cleveland Medical Center, OH.
  • Rohan Khera
    Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.

Keywords

No keywords available for this article.