The Significance of Prolonged Physical Activity in Neurogenesis and Neural Regeneration: Comparing Clinical Studies With Proposed AI-Based Framework.

Journal: Artificial organs
Published Date: Jul 21, 2025

Abstract

BACKGROUND: Adult neurogenesis is the biological process whereby neural stem cells (NSCs) differentiate into neurons and glial cells in specific areas of the adult brain. Impairments in neurogenesis may lead to many complications, including neurodegenerative illnesses and psychiatric problems. In the adult brain, new neurons are generated from neural stem or progenitor cells (NPCs) through a meticulously controlled process that governs both cell proliferation and the specification of neuronal identity.

Authors

  • Mohamed J Saadh
    Faculty of Pharmacy, Middle East University, Amman, 11831, Jordan.
  • Waleed K Abdulsahib
    Department of Pharmacology and Toxicology, College of Pharmacy, Al Farahidi University, Baghdad, Iraq.
  • Saida Saidkhodjaeva
    Department of Neurology, Pediatric Neurology and Medical Genetics, Tashkent Pediatric Medical Institute, Tashkent, Uzbekistan.
  • Gaurav Sanghvi
    Marwadi University Research Center, Department of Microbiology, Faculty of Science Marwadi University, Rajkot, Gujarat, India.
  • Suhas Ballal
    Department of Chemistry and Biochemistry, School of Sciences, JAIN (Deemed to be University), Bangalore, Karnataka, India. Electronic address: b.suhas@jainuniversity.ac.in.
  • R S K Sharma
    Department of Chemistry, Raghu Engineering College, Visakhapatnam, Andhra Pradesh, India.
  • Piyus Kumar Pathak
    Department of Applied Sciences-Chemistry, NIMS Institute of Engineering & Technology, NIMS University Rajasthan, Jaipur, India.
  • Aman Shankhyan
    Centre for Research Impact & Outcome, Chitkara University Institute of Engineering and Technology, Chitkara University, Rajpura, Punjab, 140401, India.
  • Abhinav Kumar
  • Fadhil Feez Sead
    Department of Dentistry, College of Dentistry, The Islamic University, Najaf, Iraq.
  • M V N L Chaitanya
    Department of Pharmacognosy, School of Pharmacy, Lovely Professional University, Phagwara, Punjab, India.
  • Reza Akhavan-Sigari
    Department of Neurosurgery, University Medicine Göttingen, Göttingen, Germany.

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