Attenuation of neutrophil adhesion and formation of neutrophil extracellular traps by pooled human immune globulins.

Journal: Frontiers in pharmacology
Published Date: Dec 12, 2024

Abstract

INTRODUCTION: This study investigated the efficacy of pooled human immune globulins (Flebogamma DIF) to combat the formation of neutrophil extracellular traps (NETs) and NETosis, along with neutrophil adhesion to corneal epithelial cells in response to dry eye disease relevant stimuli.

Authors

  • Vidhya R Rao
    Department of Ophthalmology, Loyola University Chicago, Maywood, IL, United States.
  • Sana Iqbal
    Graduate Program in Molecular Pharmacology and Therapeutics, Loyola University Chicago, Maywood, IL, United States.
  • Bradford A Young
    B.A.Y. Biotech Consulting, Annapolis, MD, United States.
  • Christine Mun
    Ophthalmology and Visual Sciences, University of Illinois Chicago, Chicago, IL, United States.
  • Sandeep Jain
    Ophthalmology and Visual Sciences, University of Illinois Chicago, Chicago, IL, United States.
  • Simon Kaja
    Department of Ophthalmology, Loyola University Chicago, Maywood, IL, United States.

Keywords

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