Diabetes and longitudinal changes in deep learning-derived measures of vertebral bone mineral density using conventional CT: the Multi-Ethnic Study of Atherosclerosis.

Journal: Skeletal radiology
Published Date:

Abstract

OBJECTIVE: To investigate the longitudinal association between diabetes and changes in vertebral bone mineral density (BMD) derived from conventional chest CT and to evaluate whether kidney function (estimated glomerular filtration rate (eGFR)) modifies this relationship.

Authors

  • Elena Ghotbi
    From the Russell H. Morgan Department of Radiology and Radiological Science (S.D., J.G.K., E.G., H.A.I., K.M., K.T., E.K.F.) and Department of Biomedical Engineering (W.B.Z.), Johns Hopkins University School of Medicine, 601 N Carolina St, Baltimore, MD 21287; Division of Musculoskeletal Imaging, Department of Radiology, Mayo Clinic, Rochester, Minn (F.I.B.); Department of Radiology, New York University Grossman School of Medicine, New York, NY (J.F.); Department of Radiology and Imaging, Hospital for Special Surgery, New York, NY (J.A.C.); and Department of Radiology, Quantitative Imaging Center, Boston University School of Medicine, Boston, Mass (A.G.).
  • Roham Hadidchi
    Department of Radiology and Radiologic Sciences, Johns Hopkins University, Baltimore, MD, United States.
  • Quincy A Hathaway
    Division of Exercise Physiology, West Virginia University School of Medicine, PO Box 9227, 1 Medical Center Drive, Morgantown, WV, 26505, USA.
  • Michael P Bancks
    Department of Epidemiology and Prevention, Wake Forest School of Medicine, Winston-Salem, NC, USA.
  • David A Bluemke
    From the Department of Radiology (B.A.-V.), Bloomberg School of Public Health (E.G.), and Department of Medicine, Cardiology and Radiology (J.A.C.L.), Johns Hopkins University, Baltimore, MD; George Washington University, DC (X.Y.); Office of Biostatistics, NHLBI, NIH, Bethesda, MD (C.O.W.); Department of Preventive Medicine, Northwestern University Medical School, Chicago, IL (K.L.); Department of Cardiology, Wake Forest University Health Sciences, Winston-Salem, NC (W.G.H.); Department of Biostatistics, University of Washington, Seattle (R.M.); Department of Radiology, UCLA School of Medicine, Los Angeles, CA (A.S.G.); Division of Epidemiology and Community Health, University of Minnesota, Minneapolis (A.R.F.); Departments of Medicine and Epidemiology, Columbia University, New York, NY (S.S.); and Radiology and Imaging Sciences, NIH Clinical Center, Bethesda, MD (D.A.B.).
  • R Graham Barr
    Columbia University, Division of General Medicine, New York, NY, USA.
  • Benjamin M Smith
    Department of Medicine, Columbia University Medical Center, New York, NY, United States.
  • Wendy S Post
    Division of Cardiology, Department of Medicine, Johns Hopkins University, Baltimore, MD.
  • Matthew Budoff
    4 Division of Cardiology Los Angeles Biomedical Research at Harbor-UCLA Medical Center Torrance CA.
  • João A C Lima
    From the Department of Radiology (B.A.-V.), Bloomberg School of Public Health (E.G.), and Department of Medicine, Cardiology and Radiology (J.A.C.L.), Johns Hopkins University, Baltimore, MD; George Washington University, DC (X.Y.); Office of Biostatistics, NHLBI, NIH, Bethesda, MD (C.O.W.); Department of Preventive Medicine, Northwestern University Medical School, Chicago, IL (K.L.); Department of Cardiology, Wake Forest University Health Sciences, Winston-Salem, NC (W.G.H.); Department of Biostatistics, University of Washington, Seattle (R.M.); Department of Radiology, UCLA School of Medicine, Los Angeles, CA (A.S.G.); Division of Epidemiology and Community Health, University of Minnesota, Minneapolis (A.R.F.); Departments of Medicine and Epidemiology, Columbia University, New York, NY (S.S.); and Radiology and Imaging Sciences, NIH Clinical Center, Bethesda, MD (D.A.B.). jlima@jhmi.edu.
  • Shadpour Demehri
    Department of Radiology, The Johns Hopkins Hospital, Baltimore, MD 21287.

Keywords

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