ChatGPT-4o Compared With Human Researchers in Writing Plain-Language Summaries for Cochrane Reviews: A Blinded, Randomized Non-Inferiority Controlled Trial.

Journal: Cochrane evidence synthesis and methods
Published Date: Jul 28, 2025

Abstract

INTRODUCTION: Plain language summaries in Cochrane reviews are designed to present key information in a way that is understandable to individuals without a medical background. Despite Cochrane's author guidelines, these summaries often fail to achieve their intended purpose. Studies show that they are generally difficult to read and vary in their adherence to the guidelines. Artificial intelligence is increasingly used in medicine and academia, with its potential being tested in various roles. This study aimed to investigate whether ChatGPT-4o could produce plain language summaries that are as good as the already published plain language summaries in Cochrane reviews.

Authors

  • Dagný Halla Ágústsdóttir
    Center for Perioperative Optimization, Department of Surgery, Herlev and Gentofte Hospital University of Copenhagen Copenhagen Denmark.
  • Jacob Rosenberg
  • Jason Joe Baker
    Center for Perioperative Optimization, Department of Surgery, Copenhagen University Hospital - Herlev Hospital, Denmark.

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