AI-Guided Decision Support in Acute Cardiac Care: From Chest Pain to STEMI.

Journal: Cardiology in review
Published Date:

Abstract

Artificial intelligence (AI) is rapidly transforming the landscape of acute cardiac care, offering novel opportunities to enhance diagnostic accuracy, risk stratification, and clinical decision-making. This literature review explores the current and emerging applications of AI in managing acute cardiovascular conditions, including myocardial infarction, arrhythmias, and heart failure. Methods such as machine learning, deep learning, and natural language processing have demonstrated potential in analyzing electrocardiograms, imaging, electronic health records, and wearable data to support timely and individualized care. Despite encouraging results from retrospective studies and pilot implementations, several barriers hinder broader clinical integration. Key limitations include data quality issues, lack of model transparency, clinician skepticism, regulatory uncertainties, and concerns about equity and bias. The review emphasizes the need for prospective validation, interpretability, workflow integration, and interdisciplinary collaboration to ensure safe and effective deployment. Future directions include the development of multimodal and foundation models, AI-enabled point-of-care tools, and frameworks for bias mitigation and regulatory oversight. As AI technologies evolve, their sustainable and ethical implementation will be essential to achieving meaningful improvements in patient outcomes and health system efficiency.

Authors

  • Hadrian Hoang-Vu Tran
    From the Department of Internal Medicine, Hackensack University Medical Center-Palisades Medical Center, North Bergen, NJ.
  • Audrey Thu
    Department of Medicine, Touro College of Osteopathic Medicine, New York, NY.
  • Anu Radha Twayana
    Department of Internal Medicine, Texas Tech University Health Sciences Center at Permian Basin, Odessa, TX.
  • Axel Fuertes
    From the Department of Internal Medicine, Hackensack University Medical Center-Palisades Medical Center, North Bergen, NJ.
  • Marco Gonzalez
    Neurological Institute, Cleveland Clinic, Cleveland, Ohio, USA.
  • Marina Basta
    From the Department of Internal Medicine, Hackensack University Medical Center-Palisades Medical Center, North Bergen, NJ.
  • Krutagni Adwait Mehta
    From the Department of Internal Medicine, Hackensack University Medical Center-Palisades Medical Center, North Bergen, NJ.
  • Maggie James
    From the Department of Internal Medicine, Hackensack University Medical Center-Palisades Medical Center, North Bergen, NJ.
  • Wiliam H Frishman
    Department of Medicine, New York Medical College, Valhalla, NY.
  • Wilbert S Aronow
    Department of Cardiology, Westchester Medical Center and New York Medical College, Valhalla, NY.

Keywords

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