Hyperspectral Imaging Accurately Detects Renal Malperfusion Due to High Intrarenal Pressure.

Journal: European urology open science
Published Date: Jul 11, 2025

Abstract

BACKGROUND AND OBJECTIVE: High intrarenal pressure (IRP) is a significant concern in both endoscopic procedures and acute hydronephrosis, and may cause renal parenchymal damage, forniceal rupture, and long-term impaired renal function. Its pathomechanism and effect on renal perfusion patterns remain undetermined. This study investigates the impact of elevated IRP on renal perfusion and oxygen saturation (StO) using hyperspectral imaging (HSI).

Authors

  • Luisa Egen
    Department of Urology and Urologic Surgery, University Medical Centre Mannheim, University of Heidelberg, Mannheim, Germany.
  • Moritz Hommel
    Department of Urology and Urosurgery, Medical Faculty Mannheim, University Medical Center Mannheim, Heidelberg University, Heidelberg, Germany.
  • Caelán Max Haney
    Department of Urology, University of Leipzig, Leipzig, Germany.
  • Berkin Özdemir
    Department of General, Visceral, and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany; Medical Faculty, Heidelberg University, Heidelberg, Germany.
  • Samuel Knoedler
    Division of Plastic Surgery, Department of Surgery, Yale New Haven Hospital, Yale School of Medicine, New Haven, CT, United States.
  • Jan Sellner
    Division of Intelligent Medical Systems, German Cancer Research Center (DKFZ), Heidelberg, Germany; Helmholtz Information and Data Science School for Health, Karlsruhe/Heidelberg, Germany. Electronic address: j.sellner@dkfz-heidelberg.de.
  • Silvia Seidlitz
    Division of Intelligent Medical Systems, German Cancer Research Center (DKFZ), Heidelberg, Germany; Helmholtz Information and Data Science School for Health, Karlsruhe/Heidelberg, Germany. Electronic address: s.seidlitz@dkfz-heidelberg.de.
  • Maximilian Dietrich
    Department of Anesthesiology, Heidelberg University Hospital, Heidelberg, Germany.
  • Gabriel Alexander Salg
    Department of General, Visceral, and Transplantation Surgery, Heidelberg University Hospital, Im Neuenheimer Feld 420, 69120, Heidelberg, Germany.
  • Felix Nickel
    Department of General, Visceral, and Transplantation Surgery, University of Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany. felix.nickel@med.uni-heidelberg.de.
  • Lena Maier-Hein
    German Cancer Research Center (DKFZ), Computer Assisted Medical Interventions, Heidelberg, Germany.
  • Maurice Stephan Michel
    University Hospital, Mannheim, Germany.
  • Alexander Studier-Fischer
    Department of General, Visceral, and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany; Medical Faculty, Heidelberg University, Heidelberg, Germany.
  • Karl-Friedrich Kowalewski
    Department of General, Visceral, and Transplantation Surgery, University of Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany.

Keywords

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