Association between exposure to air pollution and kidney function decline.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
Published Date: Aug 4, 2025

Abstract

BACKGROUND AND HYPOTHESIS: Chronic kidney disease is a major global health concern, with air pollution increasingly recognized as a key contributor to kidney function decline. This study hypothesizes that exposure to air pollution accelerates kidney function decline, measured by ≥ 30% or ≥ 40% reductions in estimated glomerular filtration rate (eGFR).

Authors

  • Jia-Ling Wu
    Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
  • Yu-Tzu Chang
    Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
  • Pei-Chen Lee
    Department of Public Health, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
  • Ya-Yun Cheng
    School of Medicine, College of Medicine, National Sun Yat-sen University, Kaohsiung, Taiwan.
  • Tsung Yu
    Department of Public Health, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
  • Pei-Yi Wong
    Department of Environmental and Occupational Health, National Cheng Kung University, Tainan, Taiwan.
  • Chih- Da Wu
    Department of Geomatics, National Cheng Kung University, Tainan, Taiwan.
  • Pei-Shih Chen
    Department of Public Health, College of Health Sciences, Kaohsiung Medical University, Taiwan.
  • Chung-Yi Li
    Department of Public Health, College of Medicine, National Cheng Kung University, No. 1, University Road, Tainan City 701, Taiwan.

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