Artificial intelligence-enhanced echocardiography in cardiovascular disease management.

Journal: Nature reviews. Cardiology
Published Date: Aug 5, 2025

Abstract

Artificial intelligence (AI) is transforming echocardiography, ushering in an era of improved diagnostic precision, efficiency and patient care. In this Review, we present an in-depth exploration of AI applications in echocardiography, highlighting the latest advances, practical implementations and future directions. We discuss the integration of AI throughout the echocardiographic workflow, from image acquisition and analysis to interpretation. We outline the potential of AI to automate routine measurements and calculations, enable task shifting, recognize disease-specific patterns and uncover new phenogroups that might surpass current diagnostic classifications. Moreover, we address the aspects needed to create trustworthy AI systems, through careful validation, navigating regulatory requirements and upholding ethical standards, thereby presenting a balanced perspective on the advantages and limitations of this rapidly evolving technology. Through an examination of current AI applications, clinical studies and technological breakthroughs, we offer a comprehensive understanding of the evolving role of AI in the future of echocardiography and its capacity to advance cardiovascular care, while also acknowledging the current limitations of the widespread clinical implementation of AI-supported echocardiography.

Authors

  • Peder L Myhre
    Division of Medicine, Akershus University Hospital, Lørenskog, Norway.
  • Bjørnar Grenne
    Department of Circulation and Medical Imaging, Faculty of Medicine and Health Science, Norwegian University of Science and Technology, Prinsesse Kristinas gate 3, Trondheim 7030, Norway.
  • Federico M Asch
    MedStar Health Research Institute, Washington DC (F.M.A.).
  • Victoria Delgado
    Departments of Cardiology, Heart Lung Centre, Leiden University Medical Center, Leiden, The Netherlands. Electronic address: V.Delgado@lumc.nl.
  • Rohan Khera
    Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.
  • Stephane Lafitte
    Hôpital Cardiologique Haut Lévêque, CHU de Bordeaux, CIC 0005, Pessac, France. Electronic address: stephane.lafitte@chu-bordeaux.fr.
  • Roberto M Lang
    Cardiac Imaging Center, University of Chicago Medical Center, Chicago, Illinois.
  • Patricia A Pellikka
    Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota, USA.
  • Partho P Sengupta
    Division of Cardiovascular Diseases and Hypertension, Robert Wood Johnson University Hospital, and Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA.
  • Sreekanth Vemulapalli
    Division of Cardiology, Duke University School of Medicine, Durham, NC, USA.
  • Carolyn S P Lam
    Duke-NUS Medical School, 8 College Rd, Singapore 169857, Singapore.

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