Explore the potential mechanism of Huachansu injection against osteosarcoma via metabolomics, network pharmacology and bioinformatics.

Journal: Chinese medicine
Published Date:

Abstract

AIM: Huachansu injection (HCSI) shows effective medicinal functions against osteosarcoma. This study aimed to reveal the underlying mechanisms of HCSI against osteosarcoma by integrating metabolomics, network pharmacology and bioinformatics.

Authors

  • Jingjing Meng
    Department of Pharmacy, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, China.
  • Xiangqi Zhang
    Department of Pharmacy, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, China.
  • Danfeng Xiang
    Department of Pharmacy, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, China.
  • Hanlu Liang
    Department of Pharmacy, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, China.
  • Shuai Zhao
    Xi'an Medical University, Xi'an Shaanxi, 710068, P.R.China.
  • Lingyan Xu
    Department of Pharmacy, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, China.
  • Jiao Yang
    School of Light Industry and Chemical Engineering, Dalian Polytechnic University, Dalian 116034, China; Key Laboratory of Particle & Radiation Imaging of Ministry of Education, Department of Engineering Physics, Tsinghua University, Beijing, China.
  • Junjun Chen
    Department of Intensive Care Unit, West China Hospital of Sichuan University, Chengdu 610041, China.
  • Jingxian Zhang
    Clinical Department (IVD), Shenzhen Mindray Bio-Medical Electronics Co, Ltd, Shenzhen, 518057, China.
  • Yonglong Han
    Department of Pharmacy, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, China. yonglongh@sjtu.edu.cn.

Keywords

No keywords available for this article.