The Scientific Method and Advancing Omic Technologies: Breakthroughs in Psoriatic Disease.

Journal: The Journal of rheumatology
Published Date: Aug 5, 2025

Abstract

A morning workshop addressing the topic of "What You Always Wanted to Know About Science but Were Afraid to Ask" was held at the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) 2024 annual meeting. In brief, Profs. Stephen Pennington and Nicole Ward covered the effect of recent multiomics and artificial intelligence technologies on psoriatic disease research by introducing these revolutionary advances in the context of the traditional scientific method. The workshop presented the fundamentals of genomics, transcriptomics, proteomics, and metabolomics; the limitations and challenges of these technologies; and current methods to present and interpret big data.

Authors

  • Hanna J Johnsson
    H.J. Johnsson, MBChB, PhD, University of Glasgow, School of Infection and Immunity, Glasgow, and Department of Rheumatology, Forth Valley Royal Hospital, Larbert, UK.
  • Stephen R Pennington
    School of Medicine and Medical Science, University College Dublin, Ireland.
  • Nicole L Ward
    N.L. Ward, PhD, MSc, Departments of Dermatology and Pathology, Microbiology and Immunology, and Vanderbilt Institute for Infection, Immunology and Inflammation, and Vanderbilt Center for Immunobiology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

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