Beyond genomics: a multiomics future for parasitology.

Journal: Trends in parasitology
Published Date: Aug 8, 2025

Abstract

Parasitology has long relied on genomics and transcriptomics to explore gene function, diversity, and host-parasite interactions, yet functional insight often requires deeper molecular resolution. This forum highlights advances in proteomics, metabolomics, lipidomics, and emerging technologies. We advocate an integrative multiomics approach to better understand parasite biology in context.

Authors

  • Jean-François Doherty
    Department of Zoology, The University of British Columbia, Vancouver, BC, Canada; Michael Smith Laboratories, Department of Biochemistry & Molecular Biology, The University of British Columbia, Vancouver, BC, Canada. Electronic address: jeff-doherty@hotmail.com.
  • Armando Alcázar-Magaña
    Michael Smith Laboratories, Department of Biochemistry & Molecular Biology, The University of British Columbia, Vancouver, BC, Canada.
  • Maor Arad
    Michael Smith Laboratories, Department of Biochemistry & Molecular Biology, The University of British Columbia, Vancouver, BC, Canada.
  • Jaden Chen
    Michael Smith Laboratories, Department of Biochemistry & Molecular Biology, The University of British Columbia, Vancouver, BC, Canada.
  • Lucy Shuxin Chi
    Michael Smith Laboratories, Department of Biochemistry & Molecular Biology, The University of British Columbia, Vancouver, BC, Canada.
  • Osei B Fordwour
    Michael Smith Laboratories, Department of Biochemistry & Molecular Biology, The University of British Columbia, Vancouver, BC, Canada.
  • Alessia Palumbo
    Michael Smith Laboratories, Department of Biochemistry & Molecular Biology, The University of British Columbia, Vancouver, BC, Canada.
  • Jason C Rogalski
    Michael Smith Laboratories, Department of Biochemistry & Molecular Biology, The University of British Columbia, Vancouver, BC, Canada.
  • Yuming Shi
    Michael Smith Laboratories, Department of Biochemistry & Molecular Biology, The University of British Columbia, Vancouver, BC, Canada.
  • Lucy Song
    Michael Smith Laboratories, Department of Biochemistry & Molecular Biology, The University of British Columbia, Vancouver, BC, Canada.
  • Yishan Zhang
    Department of Urology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, 107 Yanjiangxi Road, Yuexiu District, Guangzhou, 510120, Guangdong, China.
  • Huan Zhong
    Joint Surgery Department of Orthopedic Center, Affiliated Hospital of Guangdong Medical University Zhanjiang 524001, Guangdong, China. Electronic address: zhh7218@qq.com.
  • Leonard J Foster
    Michael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada.

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