Rethinking anticholinergic burden in older adults: innovative approaches to detection and management.

Journal: Expert review of clinical pharmacology
Published Date: Aug 9, 2025

Abstract

INTRODUCTION: Anticholinergic burden (AChB), the cumulative impact of medications with anticholinergic properties, is a modifiable risk factor linked to cognitive impairment, falls, and functional decline in older adults. Yet despite the availability of multiple AChB assessment tools, no consensus gold standard exists, and commonly used scales often rely on static, expert-derived drug rankings.

Authors

  • Geofrey Oteng Phutietsile
    Department of Life Sciences, University of Bath, Bath, UK.
  • Prasad S Nishtala
    Department of Life Sciences & Centre for Therapeutic Innovation, University of Bath, Bath, BA2 7AY, UK.

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