Non-invasive prediction of the secondary enucleation risk in uveal melanoma based on pretreatment CT and MRI prior to stereotactic radiotherapy.

Journal: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]
Published Date: Aug 8, 2025

Abstract

PURPOSE: The aim of this study was to develop a radiomic model to non-invasively predict the risk of secondary enucleation (SE) in patients with uveal melanoma (UM) prior to stereotactic radiotherapy using pretreatment computed tomography (CT) and magnetic resonance (MR) images.

Authors

  • Yagiz Yedekci
    Department of Radiation Oncology, Faculty of Medicine, Hacettepe University, Sihhiye, 06100, Ankara, Turkey. yagiz.yedekci@hacettepe.edu.tr.
  • Hidetaka Arimura
    Division of Medical Quantum Science, Department of Health Sciences, Faculty of Medical Sciences, Kyushu University.
  • Yu Jin
    Department of Eye Function Laboratory, Eye Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
  • Melek Tugce Yilmaz
    Department of Radiation Oncology, Faculty of Medicine, Hacettepe University, Sihhiye, 06100, Ankara, Turkey.
  • Takumi Kodama
  • Gokhan Ozyigit
    Department of Radiation Oncology, Faculty of Medicine, Hacettepe University, Sihhiye, 06100, Ankara, Turkey.
  • Gozde Yazici
    Department of Radiation Oncology, Faculty of Medicine, Hacettepe University, Ankara, Turkey.

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