Unravelling the genetic complexity of drug-resistant epilepsy: a critical narrative review.

Journal: Expert review of clinical pharmacology
Published Date: Aug 8, 2025

Abstract

INTRODUCTION: Drug-resistant epilepsy (DRE) affects 30% of epilepsy patients and represents a major therapeutic challenge. Understanding its genetic determinants is crucial for the development of effective precision medicine strategies.

Authors

  • Martina Giacon
    Department of Pharmaceutical Sciences, University of Piemonte Orientale, Novara, Italy.
  • Salvatore Terrazzino
    Department of Pharmaceutical Sciences, University of Piemonte Orientale, Novara, Italy.

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