Cognitive Phenotyping of Parkinson's Disease Patients Via Digital Analysis of Spoken Word Properties.

Journal: Movement disorders : official journal of the Movement Disorder Society
Published Date: Aug 12, 2025

Abstract

BACKGROUND: Cognitive symptoms are highly prevalent in Parkinson's disease (PD), often manifesting as mild cognitive impairment (MCI). Yet, their detection and characterization remain suboptimal because standard approaches rely on subjective impressions derived from lengthy, univariate tests.

Authors

  • Franco J Ferrante
    Centro de Neurociencias Cognitivas, Universidad de San Andrés, Buenos Aires, Argentina.
  • Daniel Escobar Grisales
    GITA Lab, Faculty of Engineering, University of Antioquia Universidad de Antioquia, Medellín, Colombia.
  • María Fernanda López
    Hospital Nacional Posadas, Buenos Aires, Argentina.
  • Pamela Lopes da Cunha
    Centro de Neurociencias Cognitivas, Universidad de San Andrés, Buenos Aires, Argentina.
  • Lucas Federico Sterpin
    Centro de Neurociencias Cognitivas, Universidad de San Andrés, Buenos Aires, Argentina.
  • Jet M J Vonk
    Memory and Aging Center, Department of Neurology, University of California San Francisco, San Francisco, California, USA.
  • Pedro Chaná Cuevas
    Centro de Trastornos del Movimiento (CETRAM), Región Metropolitana, Chile.
  • Claudio Estienne
    Instituto de Ingeniería Biomédica, Universidad de Buenos Aires, Buenos Aires, Argentina.
  • Eugenia Hesse
    Laboratory of Experimental Psychology and Neuroscience (LPEN), Institute of Cognitive and Translational Neuroscience (INCYT), INECO Foundation, Favaloro University, Buenos Aires, Argentina.
  • Lucía Amoruso
    Centro de Neurociencias Cognitivas, Universidad de San Andrés, Buenos Aires, Argentina.
  • Juan Rafael Orozco Arroyave
    GITA Lab, Faculty of Engineering, University of Antioquia Universidad de Antioquia, Medellín, Colombia.
  • Adolfo M García
    Laboratory of Experimental Psychology and Neuroscience (LPEN), Institute of Cognitive and Translational Neuroscience (INCYT), INECO Foundation, Favaloro University, Buenos Aires, Argentina.

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