Endothelin-1 in combination with CRB-65 enhance risk stratification in COVID-19 patients.

Journal: Infection
Published Date: Aug 19, 2025

Abstract

BACKGROUND: COVID-19 continuously causes severe disease conditions and significant mortality. We evaluate whether easily accessible biomarkers can improve risk prediction of severe disease outcomes.

Authors

  • Imrana Farhat
    Institute for Medical Informatics, Statistics, and Epidemiology (IMISE), University of Leipzig, Leipzig, Germany.
  • Maciej Rosolowski
    Image Biopsy Lab GmbH, Vienna, Austria.
  • Katharina Ahrens
    Department of Infectious Diseases, Respiratory Medicine and Critical Care, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
  • Jasmin Lienau
    Department of Infectious Diseases, Respiratory Medicine and Critical Care, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
  • Peter Ahnert
    Institute for Medical Informatics, Statistics, and Epidemiology (IMISE), University of Leipzig, Leipzig, Germany.
  • Mathias Pletz
    Institute of Infectious Diseases and Infection Control, Jena University Hospital, Jena, Germany mathias.pletz@med.uni-jena.de.
  • Gernot Rohde
    Dept of Respiratory Medicine, Medical Clinic I, Goethe University Hospital, Frankfurt/Main, Germany.
  • Jan Rupp
    CAPNETZ STIFTUNG, Hannover Medical School, Hannover, Germany.
  • Martin Witzenrath
    CAPNETZ STIFTUNG, Hannover Medical School, Hannover, Germany.
  • Markus Scholz
    Institute for Medical Informatics, Statistics and Epidemiology, Medical Faculty, University of Leipzig, Leipzig, Germany; LIFE Research Center of Civilization Diseases, Leipzig, Germany.

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